Macular Hole vs. Macular Degeneration: What’s the Difference?

Blurred central vision is one of the most common complaints among older adults. But not all central vision loss is the same. Two serious retinal conditions- macular hole and macular degeneration, can cause similar symptoms, yet they differ significantly in cause, progression, and treatment.

image

Understanding the distinction is critical, especially when vision is on the line. Below, we’ll compare the two in plain language, helping you know what to watch for and when to seek care.

What is a Macular Hole?

A macular hole is a small discontinuity in the center of the retina called the macula. The macula is the area of the retina responsible for fine detail and sharp central vision that we use for reading, driving, and recognizing faces. When a hole occurs, it interferes with that detail.

Common macular holes causes include:
  1. Shrinkage of the vitreous gel inside of the eye due to aging.
  2. Injury or trauma to the eye.
  3. High myopia (extreme nearsightedness).
  4. Prior eye surgery or retinal detachment.
image
Although symptoms of a macular hole eye will often develop slowly, the symptoms include:
  1. Central vision that is blurred or distorted.
  2. Straight lines appear wavy.
  3. A dark or missing spot in the center of your vision.

Usually, these macular hole symptoms will begin at first in one eye, but in 10% of cases, both eyes could be affected over time.

What Is Macular Degeneration?

Age-related macular degeneration (AMD) is a chronic, progressive disease that also affects the macula. Unlike a macular hole, it doesn’t involve a tear or break. Instead, AMD causes gradual damage to the macular tissue itself, leading to vision loss over time.

There are two types:
  1. Dry AMD (more common): Slow progression with gradual vision loss
  2. Wet AMD: More aggressive, involving abnormal blood vessels that leak fluid into the retina. This can lead to rapid vision loss.
image
AMD symptoms include:
  1. Blurred or fuzzy central vision
  2. Difficulty recognizing faces
  3. A need for brighter light when reading
  4. Straight lines appearing bent or warped

The key difference? AMD can be rapid or progress more slowly and remain stable for years, while a macular hole usually requires urgent treatment.

Macular hole stages: How It Progresses

Like many retinal disorders, macular holes exhibit a staging system:

  • Stage 1: Foveal Detachment (no full-thickness hole yet)
  • Stage 2: Small Full-Thickness Hole
  • Stage 3: Large full-thickness hole with partial vitreous separation
  • Stage 4: Full-thickness hole with complete vitreous separation

As the hole advances, treatment options start to become more critical. In the beginning stages (before full-thickness), we may monitor the hole, while in more advanced stages, the situation likely demands surgery.

Differences in Treatment: Macular Hole vs. Macular Degeneration

The primary difference between these two conditions lies in the treatment process.

Treatment for a Macular Hole:

The standard for macular hole treatment is a surgical procedure called vitrectomy. During a vitrectomy:

  1. The vitreous gel is removed from your eye.
  2. A gas bubble is placed in the eye to press the hole closed.
  3. The eye heals as the gas bubble slowly dissolves.

The surgery is called macular hole repair; the success rate is high, especially when performed early. The recovery period may require you to maintain a face-down position for a period of time. For many patients, Dr Hahn performs a surgical approach that does not require face-down positioning.

Treatment of AMD

Treatment of Macular Generation will depend on the type of AMD:

  1. Dry AMD: Typically monitored while making lifestyle changes and taking nutritional supplements (AREDS2).
  2. Wet AMD: Treated urgently with intravitreal anti-VEGF injections to stop the leaky blood vessels.

There is not a "cure" for AMD, but it can be slowed down

Macular Hole or Macular Degeneration: Which One Do I Have?

Only a retina specialist can accurately diagnose your condition through:

  • OCT (Optical Coherence Tomography): Imaging to visualize retinal layers
  • Dilated retinal exam: Direct inspection of the macula
  • Fluorescein angiography: In some cases, to assess leaking vessels (especially in AMD)

These tests help determine whether the issue is a mechanical defect (a macular hole) or a degenerative process (AMD).

Can They Coexist?

Yes, especially in older adults. Someone with macular degeneration could also develop a macular hole, particularly if their eye has structural weaknesses or has undergone prior surgery. If that happens, each condition may need to be managed separately.

When to See a Retina Specialist

If you notice:

  1. Blurry or distorted central vision
  2. A gas bubble is placed in the eye to press the hole closed.
  3. Straight lines that suddenly look wavy
  4. Trouble reading or recognizing faces

It’s time to consult a retina specialist. Dr. Paul Hahn, a board-certified expert in retinal surgery and diagnostics, provides advanced care for both macular hole and macular degeneration among other eye conditions. With decades of academic and surgical expertise, you’re in trusted hands.

Your Eyes Deserve Care
Schedule an appointment Today!